Skip Navigation LinksHome > June 2009 - Volume 30 - Issue 2 > Brain Germinoma in a Young Adult Man With Suspicion of Fatal...
American Journal of Forensic Medicine & Pathology:
doi: 10.1097/PAF.0b013e3181875ac5
Case Report

Brain Germinoma in a Young Adult Man With Suspicion of Fatal Neglect

Kibayashi, Kazuhiko MD*; Sugita, Yasuo MD†; Shojo, Hideki PhD‡; Sumida, Tomomi BMedTech‡

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Abstract

We report a forensic autopsy case of brain germinoma in a 26-year-old man who was severely wasted and initially suspected of fatal neglect. He had a history of nocturnal wandering and was confined by his parents. Neuropathological examination showed germinoma in the hypothalamus and neurohypophysis. The cause of death was certified as hypothalamo-hypophyseal insufficiency due to germinoma. Because hypothalamic lesions may dysregulate feeding behavior and sleeping rhythms, germinoma was considered the causative lesion of the anorexic wasting and nocturnal wandering. Confinement was a preventive measure of the patient's wandering. The findings in this case indicated that hypothalamic tumors should be recognized as a cause of wasting in autopsies suspected of fatal neglect.

© 2009 Lippincott Williams & Wilkins, Inc.

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