Sebaceous Hyperplasia Overlying a Dermatofibroma : The American Journal of Dermatopathology

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American Journal of Dermatopathology:

April 2006 - Volume 28 - Issue 2 - pp 155-157

doi: 10.1097/01.dad.0000175527.96873.fa

Extraordinary Case Reports

Sebaceous Hyperplasia Overlying a Dermatofibroma

Davis, Todd T. MD; Calilao, Gabriel MD; Fretzin, David MD

Abstract

Epithelial changes overlying dermatofibromas are well recognized. The presence of sebaceous differentiation overlying a dermatofibroma is unusual. We report two patients with sebaceous hyperplasia overlying a dermatofibroma and discuss possible mechanisms for induction of the epithelium and adnexa by the mesenchyme in a dermatofibroma.

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Keywords
beta catenin, dermatofibroma, fibroblasts, fibrous histiocytoma, induction, sebaceous hyperplasia, sonic hedgehog

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