Well-Differentiated Malignant CylindromaDonner, Ludvik R. MD, PhDAmerican Journal of Dermatopathology: August 2012 - Volume 34 - Issue 6 - p 677 doi: 10.1097/DAD.0b013e31824d10e1 Letters to the Editor Author Information Department of Pathology, Scott and White Memorial Hospital and Clinic, Scott, Sherwood, and Brindley Foundation, The Texas A&M Health Science Center College of Medicine, Temple, TX Article Outline To the Editor: We have described a locally invasive well-differentiated malignant cylindroma that arose in the mastoid area of an 81-year-old woman.1 She expired 10 years after surgery and did not develop any recurrences or metastases. The tumor superficially invaded the parotid gland and invaded deeply into the periparotid lymph node (Figs. 1 and 2). Although our image of the parotid gland (original Fig. 4) clearly demonstrated a mere presence of neoplastic nests in the parotid gland parenchyma and absence of a solid tumor, our diagnosis was subsequently challenged, and the tumor was proposed to represent a basal cell adenocarcinoma, a parotid gland primary.2 Unfortunately, the latter diagnosis was recently indirectly supported by another article.3 For this reason, all microscopic slides of our case were sent for review to L. Requena, Autonomous University, Madrid, and to L. Cerroni, University of Graz. The case was then discussed during the 8th Summer Academy of Dermatopathology, in Graz, Austria, in July 2011. Both experts agreed with our original diagnosis. We hope that this letter will finally dispel all doubts and uncertainty concerning our article. Figure 1 Figure 2 It is of interest that since the publication of our article, 2 cases of elderly women with locally destructive turban tumors, which were classified as benign cylindromas, were reported.4,5 Back to Top | Article Outline REFERENCES1. Donner LR, Ruff T, Diaz JA. Well-differentiated malignant cylindroma with partially preserved hyaline sheaths. A locally invasive neoplasm? Am J Dermatopathol. 1995;17:169–173. Cited Here... 2. Sangüeza OP. Well differentiated malignant cylindroma. Am J Dermatopathol. 1996;18:107–108. Cited Here... | View Full Text | PubMed | CrossRef 3. Kazakov DV, Zelger B, Rütten A, et al.. Morphologic diversity of malignant neoplasms arising in preexisting spiradenoma, cylindroma, and spiradenocylindroma based on the study of 24 cases, sporadic or occurring in the setting of Brooke–Spiegler syndrome. Am J Surg Pathol. 2009;33:705–719. Cited Here... | View Full Text | PubMed | CrossRef 4. Wyld L, Bullen S, Browning FS. Transcranial erosion of a benign dermal cylindroma. Ann Plast Surg. 1996;36:194–196. Cited Here... | View Full Text | PubMed | CrossRef 5. Friedrich ER. Dermal cylindroma of the scalp (turban tumour) and subjacent calvarian defects. Anticancer Res. 2010;30:1793–1797. Cited Here... | PubMed © 2012 Lippincott Williams & Wilkins, Inc. Article Outline REFERENCES Source Well-Differentiated Malignant Cylindroma The American Journal of Dermatopathology. 34(6):677, August 2012. Full-Size Email + Favorites Export View in Gallery Email to a Colleague Colleague's E-mail is Invalid Your Name: (optional) Your Email: Colleague's Email: Separate multiple e-mails with a (;). Message: Thought you might appreciate this item(s) I saw at The American Journal of Dermatopathology. Send a copy to your email Your message has been successfully sent to your colleague. Some error has occurred while processing your request. Please try after some time. Add Item(s) to: An Existing Folder A New Folder Folder Name: Description: The item(s) has been successfully added to "".