Review of and Comments on Article “Viral-Associated Nonmelanoma Skin Cancers: A Review”Rodriguez, Gerzain MDAmerican Journal of Dermatopathology: July 2010 - Volume 32 - Issue 5 - p 522 doi: 10.1097/DAD.0b013e3181c20f34 Letter to the Editor Author Information Article Outline School of Medicine, Universidad de La Sabana, Chía, Colombia. REFERENCE To the Editor: In the review of Dubina and Goldenberg,1 the legend for figure 1B says: “Keratinocytes show typical perinuclear halos and blue-gray pallor.” Not a single perinuclear halo is seen in the figure. Instead, what is clearly apparent is the clear, “vacuolar” appearance of nuclei of the upper malpighian layer and in the granular layer. The nuclei also show a peripheral rim of condensed chromatin. This is the typical image of flat warts of epidermodysplasia verruciformis (EV) and a clue to differentiate it from other flat warts. This image is particularly apparent in half-micron sections stained with toluidine blue (Fig. 1), and by electron microscopy correspond to fine granular material at the periphery of which viral crystals are formed (Fig. 2). Figure 1 Figure 2 Gerzain Rodriguez, MD School of Medicine, Universidad de La Sabana, Chía, Colombia Back to Top | Article Outline REFERENCE1. Dubina M, Goldenberg G. Viral-associated nonmelanoma skin cancers: a review. Am J Dermatopathol. 2009;31:561-573. Cited Here... | View Full Text | PubMed | CrossRef Copyright © 2010 Wolters Kluwer Health, Inc. All rights reserved. Article Outline REFERENCE Source Review of and Comments on Article “Viral-Associated Nonmelanoma Skin Cancers: A Review” The American Journal of Dermatopathology. 32(5):522, July 2010. Full-Size Email + Favorites Export View in Gallery Email to a Colleague Colleague's E-mail is Invalid Your Name: (optional) Your Email: Colleague's Email: Separate multiple e-mails with a (;). Message: Thought you might appreciate this item(s) I saw at The American Journal of Dermatopathology. Send a copy to your email Your message has been successfully sent to your colleague. Some error has occurred while processing your request. Please try after some time. Add Item(s) to: An Existing Folder A New Folder Folder Name: Description: The item(s) has been successfully added to "".