Skip Navigation LinksHome > October 2012 - Volume 34 - Issue 7 > Pseudotumoral Cutaneous Aspergillosis in Chronic Granulomato...
American Journal of Dermatopathology:
doi: 10.1097/DAD.0b013e3182562451
Brief Report

Pseudotumoral Cutaneous Aspergillosis in Chronic Granulomatous Disease, Report of a Pediatric Case

Khemiri, Monia MD*; El fekih, Nadia MD; Borgi, Aida MD*; Kharfi, Monia MD; Boubaker, Samir MD; Barsaoui, Sihem MD*

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Abstract

Abstract: Invasive aspergillosis is a life-threatening condition in patients with chronic granulomatous disease (CGD). Skin invasion by Aspergillus occurs most commonly by contiguity to a neighboring cavity. We describe an unusual case of invasive cutaneous aspergillosis presented as a large burgeoning tumor in a 4-year-old girl with CGD who underwent surgical treatment for bifocal osteomyelitis of the left leg. The skin invasion occurred 4 months after a “successful” treatment of invasive pulmonary aspergillosis. Atypical presentation and diagnostic difficulties are discussed. Invasive cutaneous aspergillosis may be polymorphic. The diagnosis should be considered early in the etiological investigation of any suspicious skin lesions in CGD even in uncommon aspects such as burgeoning tumors.

© 2012 Lippincott Williams & Wilkins, Inc.

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