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Nodular Lesions of Self-healing Juvenile Cutaneous Mucinosis: A Pitfall!

Barreau, Morgane MD*; Dompmartin-Blanchère, Anne MD, PhD*; Jamous, Roula MD; Chababi, Myrna MD; Soutou, Boutros MD§; Reynier-Rezzi, Judith MD; Laplaud, Anne-Laure MD*; Acher, Aurélie MD; Rod, Julien MD**; Jeanne-Pasquier, Corinne MD††; Fraitag, Sylvie MD‡‡

The American Journal of Dermatopathology: October 2012 - Volume 34 - Issue 7 - p 699–705
doi: 10.1097/DAD.0b013e3182459345
Original Study

Abstract: Self-healing juvenile cutaneous mucinosis (SHJCM) is a rare disorder of unknown origin, which occurs in children in good health. It is characterized by the multiplication of transient cutaneous papules and nodules, mainly located on the head and periarticular areas that spontaneously resolve. Histological features of SHJCM have been well described; therefore, the diagnosis is usually made easily when papules are biopsied. We report a series of 3 new cases of SHJCM presenting mainly with nodular lesions. Histological examination of these nodules showed either lesions consistent with nodular or proliferative fasciitis or nonspecific panniculitis. Mucinous deposits were present but often inconspicuous, so could be disregarded. We wanted to emphasize this misleading presentation because a biopsy for histological examination is always mandatory in cases of proliferating nodules to rule out malignant tumors. Therefore, the diagnosis always requires discussion between pathologists and clinicians to rapidly reassure the parents and avoid inappropriate therapy.

*Department of Dermatology , Centre Hospitalier Universitaire de Caen, Université de Caen Basse-Normandie, UFR de Médecine, Caen, France

Université libanaise, Beyrouth, Liban

National Pathology Institut, Université Libanaise, Beyrouth, Liban

§Department of Dermatology, Centre Hospitalier du Nord, Zgharta, Liban

Department of Dermatology, Hôpital St-Joseph, Marseille, France

Department of Dermatology, Centre Hospitalier St-Martin, Caen, France

**Department of Orthopaedics

††Department of Anatomo-pathology, Centre Hospitalier Universitaire de Caen, Université de Caen Basse-Normandie, UFR de Médecine, Caen, France

‡‡Department of Anatomo-pathology, Hôpital Necker-Enfants Malades, APHP, Université Paris-Descartes, Paris, France.

Reprints: Sylvie Fraitag, MD, Department of Anatomo-pathology, Hôpital Necker Enfants Malades, 149 Rue de Sèvres, Paris 75743, France (e-mail: sylvie.fraitag@nck.aphp.fr).

The authors declare no conflicts of interest.

© 2012 Lippincott Williams & Wilkins, Inc.