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Carcinoma Erysipeloides of Laryngeal Origin

Álvarez, María Á. PhD*; Casas, Enrique PhD*; Ruano, Juan MD*; Vélez, Antonio MD*; Salvatierra, Juan MD; Moreno, Jose C. MD*

American Journal of Dermatopathology: October 2012 - Volume 34 - Issue 7 - p 753–754
doi: 10.1097/DAD.0b013e318252f862
Brief Report

Abstract: The term “carcinoma erysipeloides” (CE) designates an uncommon form of cutaneous metastasis. CE is most often associated with carcinoma of the breast. However, there have been reports of CE from carcinoma of the uterus, prostate, lung, ovary, stomach, tonsils, thyroid, pancreas, rectum, parotid glands and melanoma. To our knowledge, CE of laryngeal origin has not been previously reported. We describe a patient diagnosed with human immunodeficiency virus and hepatitis C virus coinfection who developed a supraglottic laryngeal squamous cell carcinoma and erythematous cutaneous lesions. A skin biopsy demonstrated invasion of dilated dermal lymphatics by clusters of atypical squamous cells with polymorphic nuclei and extensive infiltration of the dermis by tumor cells. The histology of the metastatic cells was similar to that of the laryngeal carcinoma.

Departments of *Dermatology

Pathology, University Hospital “Reina Sofía,” Córdoba, Spain.

Reprints: María Á. Álvarez, PhD, Department of Dermatology, University Hospital Reina Sofía, Avda. Menéndez Pidal s/n. 14004 Córdoba, Spain (e-mail: airam_al@hotmail.com).

The authors declare no conflicts of interest.

© 2012 Lippincott Williams & Wilkins, Inc.