Reactivation of Chagas Disease by Immunosuppressive Therapy in a Patient With Systemic Lupus Erythematosus: Report of an Exceptional CaseBurgos, Lourdes Gonzalez MD*; Ortiz, Beatriz Di Martino MD*; Canese, Andrés MD†; Ojeda, Aldo MD‡; Melo, Marcia MD‡American Journal of Dermatopathology: August 2012 - Volume 34 - Issue 6 - p e84–e89 doi: 10.1097/DAD.0b013e318257f9e2 Extraordinary Case Report Abstract Author Information Abstract: Chagas disease is a zoonosis caused by the protozoan Trypanosoma cruzi. It presents as a chronic evolution and produces high morbidity and mortality in countries where the disease is endemic, as in ours. The skin disease is very rare and results from the reactivation of latent disease as a result of immunosuppression, presenting with acute, atypical, and severe lesions. We describe the case of a patient who was unaware of being a carrier of Chagas disease and presented reactivation after immunosuppressive therapy instituted to treat her systemic lupus erythematosus. *Department of Dermatology †Department of Medical Microbiology and Parasitology ‡Department of Rheumatology, Clínicas Hospital, Faculty of Medical Sciences, National University of Asuncion, Paraguay. Reprints: Beatriz Maria Di Martino Ortiz, MD, 1033 Paraguarí Street, Asuncion1325, Paraguay (e-mail: firstname.lastname@example.org). The authors declare no conflict of interest. © 2012 Lippincott Williams & Wilkins, Inc.