Skip Navigation LinksHome > April 2011 - Volume 33 - Issue 2 > Pseudoepitheliomatous Hyperplasia: A Review
American Journal of Dermatopathology:
doi: 10.1097/DAD.0b013e3181fcfb47
CME Article

Pseudoepitheliomatous Hyperplasia: A Review

Zayour, Maya MD*; Lazova, Rossitza MD†

Continued Medical Education
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Abstract

Pseudoepitheliomatous hyperplasia (PEH) is a benign condition, characterized by hyperplasia of the epidermis and adnexal epithelium, closely simulating squamous cell carcinoma. PEH may be present in a number of conditions characterized by prolonged inflammation and/or chronic infection, as well as in association with many cutaneous neoplasms. Herein, we review different inflammatory, infectious, and neoplastic skin diseases, in which florid epidermal hyperplasia is a prominent histopathologic feature, and introduce a systematic approach in the interpretation of PEH.

© 2011 Lippincott Williams & Wilkins, Inc.

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