Skip Navigation LinksHome > June 2009 - Volume 31 - Issue 4 > Primary Cutaneous Blastoid Mantle Cell Lymphoma-Case Report.
American Journal of Dermatopathology:
doi: 10.1097/DAD.0b013e31819d845a
Brief Report

Primary Cutaneous Blastoid Mantle Cell Lymphoma-Case Report.

Estrozi, Bruna MD*; Sanches, José A Jr MD, PhD†; Varela, Paulo C S MD‡; Bacchi, Carlos E MD, PhD*

Collapse Box


Mantle cell lymphoma (MCL) commonly involves extranodal sites, usually as a manifestation of disseminated disease. In rare cases, MCLs may arise as a primary tumor in the skin. Blastoid mantle cell lymphoma (BV-MCL) is a rare variant and has a more aggressive clinical course. The phenotype of BV-MCL is characterized as CD20+, CD5+, cyclin D1+, CD23, and CD10. Interphase fluorescence in situ hybridization shows a characteristic t(11;14) fusion pattern. We report a case of a BV-MCL arising in skin as primary cutaneous MCL with the characteristic immunophenotype and translocation.

© 2009 Lippincott Williams & Wilkins, Inc.


Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.