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Metastatic Merkel Cell Carcinoma With Positive Expression of Thyroid Transcription Factor-1-A Case Report

Sierakowski, Adam MBBS, BSc(Hons), MRCS; Al-Janabi, Khalid MB Chb, FRCPath; Dam, Helena van MBBCh, MRCS, MSc; Sood, Manu MS Mch(Plast)

The American Journal of Dermatopathology: June 2009 - Volume 31 - Issue 4 - p 384-386
doi: 10.1097/DAD.0b013e31819821e8
Extraordinary Case Report

We report on a case of metastatic Merkel cell carcinoma in a 74-year-old patient with positive staining for thyroid transcription factor-1. This represents a new immunohistochemical staining pattern for Merkel cell carcinoma and has implications regarding the accurate diagnosis of this tumor type.

From the St. Andrew's Centre for Plastic Surgery, Broomfield Hospital, Chelmsford, Essex, United Kingdom, CM1 7ET.

Reprints: Adam Sierakowski, MBBS, BSc(Hons), MRCS, St. Andrew's Centre for Plastic Surgery, Court Road, Broomfield, Chelmsford, Essex CM1 7ET, United Kingdom (e-mail: adamsiera@yahoo.co.uk).

© 2009 Lippincott Williams & Wilkins, Inc.