Skip Navigation LinksHome > June 2009 - Volume 31 - Issue 4 > Angiomatosis: A Case With Metaplastic Ossification
American Journal of Dermatopathology:
doi: 10.1097/DAD.0b013e318185d1ec
Extraordinary Case Report

Angiomatosis: A Case With Metaplastic Ossification

Arsenovic, Nebojsa Neca MD*; Sen, Soumadri MD*; Patel, Jenish MD*; Terzic, Milan MD, PhD†; Reed, Malcolm MD*

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Abstract

Angiomatosis is defined as a hemangioma that affects a large segment of the body in a contiguous fashion, either by vertical extension to involve multiple tissue planes (eg, skin, subcutis, muscle, bone) or by crossing muscle compartments to involve similar tissue types (eg, multiple muscles). Such lesions usually present in the first 2 decades of life and have a highly characteristic but not totally specific histological pattern. Histology usually shows a haphazard mixture of small and medium-sized vessels, fat, connective tissue, and lymphatics. Large amounts of mature fat frequently accompany the vascular elements, suggesting that the lesion may possibly be a more generalized mesenchymal proliferation rather than an exclusively vascular lesion. Here we present what we believe to be the first case of angiomatosis showing osseous metaplasia.

© 2009 Lippincott Williams & Wilkins, Inc.

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