Skip Navigation LinksHome > October 2008 - Volume 30 - Issue 5 > Vitiligo-like Primary Melanoma
American Journal of Dermatopathology:
doi: 10.1097/DAD.0b013e318177a423
Extraordinary Case Report

Vitiligo-like Primary Melanoma

Lugo-Somolinos, Aída MD*; Sánchez, Jorge L MD†; Garcia, María E MD†

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Abstract

Depigmented or hypopigmented macules and patches have been described in association to primary and metastatic melanoma. Primary melanoma presenting at the onset as a vitiliginous patch without histopathological evidence of regression seems to be a rare event. We report 2 patients with melanoma in situ that expressed clinically as vitiligo-like patches and review the possible immunologic mechanisms responsible for this unusual presentation.

© 2008 Lippincott Williams & Wilkins, Inc.

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