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Syringocystadenoma Papilliferum With Sebaceous Differentiation in an Intradermal Tubular Apocrine Component. Report of a Case

Vazmitel, Marina MD*; Michal, Michal MD†; Mukensnabl, Petr MD†; Kazakov, Dmitry V MD, PhD†

American Journal of Dermatopathology:
doi: 10.1097/DAD.0b013e31815c4cf4
Extraordinary Case Report

Syringocystadenoma papilliferum is a benign tumor most commonly located on the scalp or face, and it often arises within a nevus sebaceus of Jadassohn. We describe a 61-year-old man with syringocystadenoma papilliferum developing within a nevus sebaceus with sebaceous differentiation in an intradermal tubular apocrine component of the syringocystadenoma papilliferum. Although some adnexal neoplasms that develop in association with a nevus sebaceus may exhibit conjoint sebaceous, follicular, or apocrine differentiation, reflecting close embryological relations of the folliculosebaceous-apocrine unit, the feature we report on has not previously been described to the best of our knowledge.

Author Information

From the *Department of Pathology, Academy of Postgraduate Studies, Minsk, Republic of Belarus; and †Sikl's Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic.

Reprints: Dmitry V. Kazakov, MD, PhD, Sikl's Department of Pathology, Charles University, Medical Faculty Hospital, Alej Svobody 80, 304 60 Pilsen, Czech Republic (e-mail:

© 2008 Lippincott Williams & Wilkins, Inc.