A cutaneous metaplastic synovial cyst is a rare entity that is probably caused by trauma or surgery. We report the second case of cutaneous metaplastic synovial cyst in a child with Ehlers-Danlos syndrome. His father is also affected with Ehlers-Danlos syndrome, and his diagnosis is substantiated by the demonstration of reduced synthesis of collagen type V.
From the *Pediatria, Ospedale Castelli, ASL 14 Regione Piemonte, Verbania; †Dipartimento di Biochimica “A Castellani” Università di Pavia, Pavia; ‡Anatomia ed Istologia Patologica, Ospedale S, Andrea, Vercelli; §Chirurgia Generale, Ospedale SS. Pietro e Paolo, Borgosesia; ¶Dermatologia, Ospedale S. Andrea, Vercelli; and ‖Genetica Medica, Università di Pavia e IRCCS S.Matteo, Pavia, Italy.
Reprints: Cesare Danesino, MD, Genetica Medica, Via Forlanini 14, 27100 Pavia, Italy (e-mail: firstname.lastname@example.org).