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American Journal of Dermatopathology:
doi: 10.1097/
Extraordinary Case Reports

Incidental Granular Parakeratosis Associated With Dermatomyositis

Pock, Lumír MD*; Hercogova`, Jana MD

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A 43-year-old patient presented with a 4-month history of intermittently occurring symmetrical and slightly scaling erythematous plaques in his zygomatic regions. Because of polymyositis in the patient's history, the skin lesions were thought to be a manifestation of dermatomyositis. The skin biopsy revealed a sparse superficial perivascular infiltrate of lymphocytes, which was associated with telangiectases and both discrete vacuolar alteration and smudging of the dermal-epidermal junction. These findings were consonant with dermatomyositis. In addition to these features focal granular parakeratosis was present. The histopathologic presence of granular parakeratotic corneocytes above a zone of orthokeratosis and the absence of clinical features of granular parakeratosis indicate the granular parakeratosis is incidental.

© 2006 Lippincott Williams & Wilkins, Inc.


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