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Incidental Granular Parakeratosis Associated With Dermatomyositis

Pock, Lumír MD*; Hercogova`, Jana MD

American Journal of Dermatopathology: April 2006 - Volume 28 - Issue 2 - pp 147-149
doi: 10.1097/01.dad.0000171604.71057.3e
Extraordinary Case Reports

A 43-year-old patient presented with a 4-month history of intermittently occurring symmetrical and slightly scaling erythematous plaques in his zygomatic regions. Because of polymyositis in the patient's history, the skin lesions were thought to be a manifestation of dermatomyositis. The skin biopsy revealed a sparse superficial perivascular infiltrate of lymphocytes, which was associated with telangiectases and both discrete vacuolar alteration and smudging of the dermal-epidermal junction. These findings were consonant with dermatomyositis. In addition to these features focal granular parakeratosis was present. The histopathologic presence of granular parakeratotic corneocytes above a zone of orthokeratosis and the absence of clinical features of granular parakeratosis indicate the granular parakeratosis is incidental.

*Dermatopathologic Laboratory, Prague, Czech Republic

Department of Dermatology and Venereology, 2nd Medical Faculty, Charles University, Prague, Czech Republic

Reprints: Dr Lumír Pock, Dermatohistopathologic Laboratory, Mazurska` 484 181 00, Prague 8, Czech Republic (e-mail: lumir.pock@volny.cz).

© 2006 Lippincott Williams & Wilkins, Inc.