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Proliferation of Eccrine Sweat Ducts Associated With Heterotopic Neural Tissue (Nasal Glioma)

Gambini, Claudio M.D.; Rongioletti, Franco M.D.; Rebora, Alfredo M.D.

American Journal of Dermatopathology: April 2000 - Volume 22 - Issue 2 - pp 179-182
Extraordinary Case Reports

The term “nasal glioma” refers to the presence of heterotopic neural tissue, mainly glial in nature, at or near the root of the nose. We describe a case in which all three components of neural tissue, that is, leptomeninges, glia, and neurons, were present, associated with sweat-duct hyperplasia. Proliferation of sweat ducts is a reactive process in some benign and malignant neoplasms, hamartomas, and cysts. This is the first documented case of hyperplasia of eccrine ductal epithelium induced by nasal glioma.

From the Division of Pathology, Gaslini Hospital (C.G.) and the Department of Endocrinology and Metabolic Diseases, Section of Dermatology, University of Genoa (F.R., A.R.), Genoa, Italy.

Address correspondence and reprint requests to Franco Rongioletti, M.D., Department of Endocrinology and Metabolic Diseases, Section of Dermatology, University of Genoa, Viale Benedetto XV, 7, Genoa, Italy.

© 2000 Lippincott Williams & Wilkins, Inc.