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American Journal of Therapeutics:
Symposium: Blood Transfusions and Solutions

Blood Substitutes and Oxygen Therapeutics: An Overview and Current Status

Jahr, Jonathan S. *; Nesargi, Susmita B.2,3; Lewis, Kenneth2,3; Johnson, Calvin2,3

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This review article discusses the development and implementation of a number of blood substitutes, including hemoglobin-based oxygen carriers (HBOCs) and perfluorocarbons. This review article will introduce the reader to blood substitutes by discussing an overview of an ideal blood substitute, the history of HBOCs and perfluorocarbons, strategies of oxygen carrying, side effects of HBOCs and perfluorocarbons, current clinical trials, and the future of blood substitutes.

© 2002 Lippincott Williams & Wilkins, Inc.


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