Skip Navigation LinksHome > April 2009 - Volume 33 - Issue 4 > Intramedullary Amputation Neuromas Associated With Spinal Ep...
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American Journal of Surgical Pathology:
doi: 10.1097/PAS.0b013e31818fe3c9
Original Articles

Intramedullary Amputation Neuromas Associated With Spinal Ependymomas

Johnson, Michael W. MD, PhD; Burger, Peter C. MD

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We report 5 spinal intramedullary masses containing combined ependymoma and traumatic neuroma. The ependymomas, grade II “cellular” types, were intermixed with or separate from wavy, vaguely fascicular tissue that contained multiple axons immunoreactive for neurofilament protein. The neuromas presumably arose from small perivascular nerve twigs that have been implicated in the pathogenesis of intramedullary neuromas in non-neoplastic spinal diseases. Pathologists should be aware of this distinctive intramedullary tissue that is not to be confused with a neoplasm.

© 2009 Lippincott Williams & Wilkins, Inc.


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