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American Journal of Physical Medicine & Rehabilitation:
doi: 10.1097/PHM.0b013e31815b5e1a
Case Reports: Multiple Sclerosis

Rehabilitation of Neuromyelitis Optica (Devic Syndrome): Three Case Reports

Schreiber, Adam L. DO, MA; Fried, Guy W. MD; Formal, Christopher S. MD; DeSouza, Bryan X. MD

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Schreiber AL, Fried GW, Formal CS, DeSouza BX: Rehabilitation of neuromyelitis optica (Devic syndrome): three case reports. Am J Phys Med Rehabil 2008;87:144–148.

We describe the inpatient clinical rehabilitation course of three patients with neuromyelitis optica (NMO; Devic syndrome). These patients had varying functional deficits. Each patient improved in several functional independence measures (FIM domains) but had minimal to no progress in other domains after acute rehabilitation stays between 1 and 1.5 mos. NMO is a severe central nervous system demyelinating syndrome distinct from MS, characterized by optic neuritis, myelitis, and at least two of three criteria: longitudinally extensive cord lesion, MRI nondiagnostic for multiple sclerosis, or NMO-IgG seropositivity. Persons with NMO may demonstrate improved function with rehabilitation efforts; though gains may be lost to relapse. Future immunomodulatory intervention may augment the benefits of rehabilitation.

© 2008 Lippincott Williams & Wilkins, Inc.


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