Skip Navigation LinksHome > May 2004 - Volume 83 - Issue 5 > Preganglionic Approach to Transforaminal Epidural Steroid In...
American Journal of Physical Medicine & Rehabilitation:
Visual Vignette

Preganglionic Approach to Transforaminal Epidural Steroid Injections

Lew, Henry L. MD, PhD; Coelho, Paul MD; Chou, Larry H. MD

Free Access
Article Outline
Collapse Box

Author Information

Physical Medicine and Rehabilitation Service, VA Palo Alto Health Care System, Stanford University School of Medicine, Palo Alto, California

Kaiser Permanente Richmond/Oakland, Oakland, California

University of Pennsylvania, Philadelphia, Pennsylvania

Several studies have demonstrated the efficacy of transforaminal epidural steroid injections (TFESI) for the treatment of lumbosacral radicular pain. 1–4 Using standard TFESI technique, the spinal needle is positioned within the “safe triangle” (bordering the pedicle, the exiting nerve root, and the posterolateral border of the vertebral body), with the bevel below the inferior aspect of the pedicle. In a selective nerve root block, the injectate typically bathes the epidural space around the dorsal root ganglion and descends along the distal aspect of the nerve root (Fig. 1, bottom arrow). Ideally, if there is no stenosis, and the needle tip is appropriately positioned, the injectate may spread rostrally to the epidural portion of the preganglionic nerve root as well (Fig. 1, top arrow).

Figure 1
Figure 1
Image Tools

In most cases of lumbosacral radiculopathy secondary to stenosis or a herniated disc, the site of impingement usually lies at the level of the supra-adjacent intervertebral disc, which is rostral to the conventional lumbar TFESI bevel position. However, one cannot always guarantee a rostral spread of injectate to bathe the epidural/preganglionic portion of the nerve root. As an example, in treating a right S1 radiculopathy with TFESI at the exiting nerve root location (S1 foramen), the injectate failed to ascend to the L5-S1 disc level (Fig. 2, bottom arrow). In situations like this, one may wish to consider a supplementary preganglionic TFESI approach. The fluoroscopic landmarks utilized for needle positioning are similar to those used for intradiscal procedures (lateral to the superior articular process and parallel to the superior endplate of the vertebral body). The final needle position is at the inferior aspect of the supra-adjacent neural foramen, with the bevel immediately dorsal to the annulus/posterior longitudinal ligament. Injection at this position places the aliquot at the epidural preganglionic site of neural impingement, where the traversing nerve root is in closest proximity to the disc. The injectate may also descend to the intraforaminal and epidural portion of the exiting nerve root (Fig. 2, top arrow).

Figure 2
Figure 2
Image Tools

Theoretical advantages of the preganglionic TFESI technique include placing of the injectate closer to the site of neural impingement and providing a more effective washout of inflammatory disc material. Perhaps this methodology may be useful as a supplementary injection technique to the conventional TFESI, especially in patients who demonstrate poor rostral spread of injectate toward the epidural/preganglionic portion of the nerve root. A prospective, randomized, controlled trial may be needed to verify its clinical efficacy and further define its utility.

Back to Top | Article Outline


1. Botwin KP, Gruber RD, Bouchlas CG, et al: Fluoroscopically guided lumbar transformational epidural steroid injections in degenerative lumbar stenosis: An outcome study. Am J Phys Med Rehabil 2002;81:898–905

2. Slipman CW, Chow DW: Therapeutic spinal corticosteroid injections for the management of radiculopathies. Phys Med Rehabil Clin N Am 2002;13:697–711

3. Vad VB, Bhat AL, Lutz GE, et al: Transforaminal epidural steroid injections in lumbosacral radiculopathy: A prospective randomized study. Spine 2002;27:11–6

4. Nelemans PJ, deBie RA, deVet HC, et al: Injection therapy for subacute and chronic benign low back pain. Spine 2001;26:501–15

Cited By:

This article has been cited 10 time(s).

Korean Journal of Radiology
Epidural steroid injection for lumbosacral radiculopathy
Sung, MS
Korean Journal of Radiology, 7(2): 77-79.

Korean Journal of Radiology
Transforaminal epidural steroid injection for lumbosacral radiculopathy: Preganglionic versus conventional approach
Lee, JW; Kim, SH; Choi, JY; Yeom, JS; Kim, KJ; Chung, SK; Kim, HJ; Kim, C; Kwack, KS; Kwon, JW; Moon, SG; Jun, WS; Kang, HS
Korean Journal of Radiology, 7(2): 139-144.

Neurology India
Transforaminal epidural steroid injection via a preganglionic approach for lumbar spinal stenosis and lumbar discogenic pain with radiculopathy
Kabatas, S; Cansever, T; Yilmaz, C; Kocyigit, OI; Coskun, E; Demircay, E; Akar, A; Caner, H
Neurology India, 58(2): 248-252.
American Journal of Roentgenology
Therapeutic effect and outcome predictors of sciatica treated using transforaminal epidural steroid injection
Lee, JW; Kim, SH; Lee, IS; Choi, JA; Choi, JY; Hong, SH; Kang, HS
American Journal of Roentgenology, 187(6): 1427-1431.
Spine Journal
Blind Man's Bluff
Smuck, M
Spine Journal, 9(6): 518-519.
Effectiveness of transforaminal epidural steroid injection by using a preganglionic approach: A prospective randomized controlled study
Jeong, HS; Lee, JW; Kim, SH; Myung, JS; Kim, JH; Kang, HS
Radiology, 245(2): 584-590.
American Journal of Neuroradiology
Comparison of the temporary diagnostic relief of transforaminal epidural steroid injection approaches: Conventional versus posterolateral technique
Lee, IS; Kim, SH; Lee, JW; Hong, SH; Choi, JY; Kang, HS; Song, JW; Kwon, AK
American Journal of Neuroradiology, 28(2): 204-208.

Pain Physician
Transforaminal Hypertonic Saline for the Treatment of Lumbar Lateral Canal Stenosis: A Double-Blinded, Randomized, Active-Control Trial
Koh, WU; Choi, SS; Park, SY; Joo, EY; Kim, SH; Lee, JD; Shin, JY; Suh, JH; Leem, JG; Shin, JW
Pain Physician, 16(3): 197-211.

Pain Physician
The Efficacy of Transforaminal Epidural Steroid Injection by the Conventional Technique in Far-Lateral Herniation of Lumbar Disc
Kim, HJ; Park, JH; Shin, KM; Kang, SS; Kim, IS; Hong, SJ; Song, CK; Park, JC; Yeom, JS
Pain Physician, 15(5): 415-420.

Incidence and Root Cause Analysis of Wrong-site Pain Management Procedures: A Multicenter Study
Cohen, SP; Hayek, SM; Datta, S; Bajwa, ZH; Larkin, TM; Griffith, S; Hobelmann, G; Christo, PJ; White, R
Anesthesiology, 112(3): 711-718.
PDF (281) | CrossRef
Back to Top | Article Outline

© 2004 Lippincott Williams & Wilkins, Inc.


Article Tools