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American Journal of Physical Medicine & Rehabilitation:
doi: 10.1097/PHM.0b013e31815e6680
Original Research Article: Stroke

Effects of a New Radio Frequency–Controlled Neuroprosthesis on Gait Symmetry and Rhythmicity in Patients with Chronic Hemiparesis

Hausdorff, Jeffrey M. PhD; Ring, Haim MD, MSc

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Hausdorff JM, Ring H: Effects of a new radio frequency–controlled neuroprosthesis on gait symmetry and rhythmicity in patients with chronic hemiparesis. Am J Phys Med Rehabil 2008;87:4–13.

Objective: To assess the effects of a new neuroprosthesis (NESS L300) designed to ameliorate foot drop on gait symmetry and rhythmicity during walking.

Design: Twenty-four patients (mean age: 54.0 ± 13.5 yrs) with chronic hemiparesis (5.8 ± 5.2 yrs) whose walking was impaired by foot drop. Subjects walked for 6 mins while wearing force-sensitive insoles, once with and once without the neuroprosthesis, in randomized order. Additional assessments with the neuroprosthesis were conducted after using the device for 4 and 8 wks. Walking speed, swing, and stride time were determined, along with a gait asymmetry index and stride time variability—both markers of gait stability and fall risk.

Results: While wearing the neuroprosthesis, the gait asymmetry index instantly improved by 28% (from 0.58 ± 0.30 to 0.42 ± 0.22) and by 45% (to 0.32 ± 0.20; P < 0.001) after 8 wks. Stride time variability decreased by 23% immediately (from 5.7 ± 2.9% to 4.4 ± 1.3%) and by 33% (to 3.8 ± 1.4%; P = 0.002) after 8 wks. Walking speed improved initially by 17% (from 0.53 ± 0.24 to 0.62 ± 0.22 m/sec) and after 8 wks by 34% (to 0.71 ± 0.25 m/sec; P < 0.001).

Conclusions: The studied neuroprosthesis enhances gait and improves dynamic stability in chronic hemiparetic patients, supporting the idea that this is a viable treatment option in the rehabilitation of patients with foot drop.

© 2008 Lippincott Williams & Wilkins, Inc.


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