Introduction to Nanotechnology: Potential Applications in Physical Medicine and RehabilitationGordon, Assaf T. MD; Lutz, Greg E. MD; Boninger, Michael L. MD; Cooper, Rory A. PhDAmerican Journal of Physical Medicine & Rehabilitation: March 2007 - Volume 86 - Issue 3 - p 225-241 doi: 10.1097/PHM.0b013e318031ee1a Invited Review: Nanotechnology Abstract Author Information Gordon AT, Lutz GE, Cooper RA, Boninger ML: Introduction to nanotechnology: potential applications in physical medicine and rehabilitation. Am J Phys Med Rehabil 2007;86:225–241. Nanotechnology is a scientific movement that has the potential to transform the diagnosis and treatment of disease in the 21st century. The area of investigation is defined by the study, design, manipulation, manufacture, and control of materials or devices by physical or chemical means at resolutions on the order of one billionth of a meter. The potential for a wide range of clinical applications makes a basic understanding of nanotechnology important to physiatrists. This review presents an introduction to nanotechnology and discusses key developments in tissue engineering, drug delivery, imaging, diagnostics, surface texturing, and biointerfaces that could impact the practice of physiatry in the future. Department of Physical Medicine and Rehabilitation, New York University, Rusk Institute, New York, New York (ATG); Department of Physical Medicine and Rehabilitation, New York–Presbyterian University Hospitals of Columbia and Cornell, Hospital for Special Surgery, New York, New York (GEL); and University of Pittsburgh, Departments of PM&R, Rehabilitation, Science & Technology, and Bioengineering, Pittsburgh, Pennsylvania (RAC, MLB). All correspondence and requests for reprints should be addressed to Assaf T. Gordon, MD, email@example.com © 2007 Lippincott Williams & Wilkins, Inc.