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Effects of Regular Exercise Training on Skeletal Muscle Contractile Function

Fitts, Robert H. PhD

American Journal of Physical Medicine & Rehabilitation: April 2003 - Volume 82 - Issue 4 - pp 320-331
Literature Review: Cellular & Molecular Adaptations

Fitts RH: Effects of regular exercise training on skeletal muscle contractile function. Am J Phys Med Rehabil 2003;82:320–331.

Skeletal muscle function is critical to movement and one’s ability to perform daily tasks, such as eating and walking. One objective of this article is to review the contractile properties of fast and slow skeletal muscle and single fibers, with particular emphasis on the cellular events that control or rate limit the important mechanical properties. Another important goal of this article is to present the current understanding of how the contractile properties of limb skeletal muscle adapt to programs of regular exercise.

From the Department of Biology, Marquette University, Milwaukee, Wisconsin.

Supported, in part, by National Aeronautics and Space Administration grant NAG 9-1156.

Presented at the State of the Science Roundtable 2001: Role of Physical Activity and Exercise Training in Neuromuscular Diseases, San Diego, California, September 30 through October 3, 2001, a conference sponsored by the National Institute on Disability and Rehabilitation Research and Training Center in Neuromuscular Diseases at the University of California-Davis, University of California-Davis Exercise Biology Program, and the Muscular Dystrophy Association.

All correspondence and requests for reprints should be addressed to: Robert H. Fitts, PhD, Marquette University, Department of Biology, Wehr Life Sciences Building, P.O. Box 1881, Milwaukee, WI 53201-1881.

© 2003 Lippincott Williams & Wilkins, Inc.