Enter your Email address:
Wolters Kluwer Health may email you for journal alerts and information, but is committed
to maintaining your privacy and will not share your personal information without
Mahon, Suzanne M. DNSc, RN, AOCN, APNG; Kaplan, Marcelle MS, RN, AOCN, CBCN
Suzanne M. Mahon, DNSc, RN, AOCN, APNG
Marcelle Kaplan, MS, RN, AOCN, CBCN
We would like to thank Diane S. Aschenbrenner for her detailed discussion of the unexpected FDA approval of paroxetine as the first nonhormonal drug treatment for postmenopausal hot flashes (Drug Watch, October 2013). This is good news, as there's an overwhelming need for safe and effective nonhormonal therapies. Yet, a large subgroup of women likely to experience hot flashes—those taking tamoxifen for the prevention or treatment of breast cancer—won't be able to take advantage of this new treatment option.
Paroxetine is not recommended in individuals taking tamoxifen because it interferes with the activation of tamoxifen's active agent. When used concomitantly with tamoxifen, paroxetine has been associated with an increase in breast cancer–related deaths.1 Paroxetine's label contains a warning that its use may reduce the effectiveness of tamoxifen, and current oncology guidelines advise caution when coadministering these drugs.2
© 2014 Lippincott Williams & Wilkins. All rights reserved.
Colleague's E-mail is Invalid
Your Name: (optional)
Separate multiple e-mails with a (;).
Thought you might appreciate this item(s) I saw at AJN The American Journal of Nursing.
Send a copy to your email
Your message has been successfully sent to your colleague.
Some error has occurred while processing your request. Please try after some time.
An Existing Folder
A New Folder
The item(s) has been successfully added to "".
Login with your LWW Journals username and password.
Username or Email:
Enter and submit the email address you registered with. An email with instructions to reset your password will be sent to that address.
Link to reset your password has been sent to specified email address.
What does "Remember me" mean?
By checking this box, you'll stay logged in until you logout. You'll get easier access to your articles, collections,
media, and all your other content, even if you close your browser or shut down your
To protect your most sensitive data and activities (like changing your password),
we'll ask you to re-enter your password when you access these services.
What if I'm on a computer that I share with others?
If you're using a public computer or you share this computer with others, we recommend
that you uncheck the "Remember me" box.
Save my selection
Article Level Metrics