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AJN, American Journal of Nursing:
doi: 10.1097/01.NAJ.0000451677.35953.ab
Drug Watch

Labeling Changes for Topiramate (Topamax) and Doripenem (Doribax)

Aschenbrenner, Diane S. MS, RN

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* The Food and Drug Administration (FDA) has approved the antiepileptic drug topiramate (Topamax) for a new indication, the prevention of migraines in adolescents ages 12 to 17.

* The FDA has added a new warning to the labeling of the antibiotic doripenem (Doribax), which now warns that the drug increases the risk of death if used to treat ventilator-associated bacterial pneumonia, an off-label use.

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