* The tetracycline antibiotic tigecycline (Tygacil) now carries a boxed warning that iv use of the drug increases the risk of death. The exact cause of the increased risk hasn't been determined.
* Use of tigecycline should be limited to approved clinical indications when other forms of treatment aren't suitable. Tigecycline shouldn't be used in the treatment of diabetic foot infection or hospital-acquired pneumonia.
Diane S. Aschenbrenner recently retired as course coordinator for undergraduate pharmacology at Johns Hopkins University School of Nursing in Baltimore, MD. She also coordinates Drug Watch: firstname.lastname@example.org.