* There appears to be a relationship between the antihypertensive drug olmesartan medoxomil and spruelike enteropathy. This condition develops after long-term use of the drug, usually two years or more after the start of therapy.
* Patients who develop diarrhea and weight loss but don't have celiac sprue should be taken off olmesartan.
Diane S. Aschenbrenner recently retired as course coordinator for undergraduate pharmacology at Johns Hopkins University School of Nursing in Baltimore, MD. She also coordinates Drug Watch: firstname.lastname@example.org.