* Perampanel (Fycompa) has been approved to treat partial-onset seizures (with or without generalized seizures) when other antiepileptic therapy hasn't been sufficient.
* Perampanel, which is used in addition to other antiepileptic medications, can induce serious or even life-threatening psychiatric or behavioral changes. These adverse effects are more likely to occur during dosage escalation or when larger doses are prescribed.
Diane S. Aschenbrenner is the course coordinator for undergraduate pharmacology at Johns Hopkins University School of Nursing in Baltimore, MD. She also coordinates Drug Watch: firstname.lastname@example.org.