You could be reading the full-text of this article now if you...

If you have access to this article through your institution,
you can view this article in

New Drug Treats Metastatic Melanoma

Aschenbrenner, Diane S. MS, RN

AJN, American Journal of Nursing:
doi: 10.1097/01.NAJ.0000399309.83160.a5
Drug Watch

* The newest monoclonal antibody, ipilimumab (Yervoy), is a targeted therapy for late-stage (metastatic) melanoma and is the first drug shown to prolong life in patients with this condition.

* The drug's most common adverse effects include fatigue, diarrhea, pruritus, rash, and colitis.

* Ipilimumab can have serious and even life-threatening immune-mediated adverse effects, such as enterocolitis, hepatitis, dermatitis, neuropathy, and endocrinopathy.

Author Information

Diane S. Aschenbrenner is the course coordinator for undergraduate pharmacology at Johns Hopkins University School of Nursing in Baltimore, MD. She also coordinates Drug Watch:

© 2011 Lippincott Williams & Wilkins, Inc.