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New Warning for HIV Drug Saquinavir

Aschenbrenner, Diane S. MS, APRN-BC

AJN, American Journal of Nursing: February 2011 - Volume 111 - Issue 2 - p 27
doi: 10.1097/01.NAJ.0000394288.47954.8c
Drug Watch

* Potentially dangerous electrocardiographic changes may occur when the HIV protease inhibitors saquinavir (Invirase) and ritonavir (Norvir) are taken together.

* Either a prolonged QT interval, which can lead to torsades de pointes, or a prolonged PR interval, which can lead to heart block, can occur.

Diane S. Aschenbrenner is the course coordinator for undergraduate pharmacology at Johns Hopkins University School of Nursing in Baltimore, MD. She also coordinates Drug Watch:

© 2011 Lippincott Williams & Wilkins, Inc.