Five percent of 145 HIV-1 infected men enrolled in an assisted reproductive technology (ART) program harbored detectable HIV-1 RNA in semen, although they had no other sexually transmitted disease and their blood viral load was undetectable for at least 6 months under antiretroviral treatment. This result justifies measuring HIV-1 RNA in semen before the ART process and suggests that a residual risk of transmission has to be mentioned to the patients who would like to have unprotected sexual intercourse.
aUPMC Univ Paris 06, EA 2387, France
bAP-HP, Hôpital Pitié Salpêtrière, Laboratoire de Virologie, France
cAP-HP, Hôpital Pitié Salpêtrière, Service de Maladies Infectieuses, France
dINSERM U720, France
eAP-HP, Hôpital Pitié Salpêtrière, Service de Gynécologie-Obstétrique, France
fAP-HP, Hôpital Pitié Salpêtrière, Service de Médecine Interne, France
gAP-HP, Hôpital Pitié Salpêtrière, Unité de Biologie de la Reproduction, France
hAP-HP, Hôpital Bichat-Claude Bernard, Service de Pharmacie, France
iUPMC Univ Paris 06, EA 1533, Paris, France.
Correspondence to Anne-Geneviève Marcelin, PharmD, PhD, Department of Virology, 83 boulevard de l'hôpital, 75013 Paris, France. Tel: +33 1 42177401; fax: +33 1 42177411; e-mail: firstname.lastname@example.org