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AIDS:
doi: 10.1097/QAD.0000000000000342
Research Letters

HIV-1 superinfection with a triple-class drug-resistant strain in a patient successfully controlled with antiretroviral treatment

Castro, Erikaa,c; Zhao, Hongb; Cavassini, Matthiasa; Mullins, James I.b; Pantaleo, Giuseppec; Bart, Pierre-Alexandrec,d

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Abstract

We report a case of HIV-1 superinfection (HSI) with a clade B, triple-class resistant virus in a patient successfully controlling viremia with continuous combination antiretroviral therapy started 8 years earlier during primary HIV infection. The course of HIV infection prior to HSI was monitored in both the source partner and recipient (8 and 11 years, respectively) and 4 years following HSI. This case report demonstrates re-infection with HIV-1 despite effective combination antiretroviral therapy.

© 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins

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