We report a case of HIV-1 superinfection (HSI) with a clade B, triple-class resistant virus in a patient successfully controlling viremia with continuous combination antiretroviral therapy started 8 years earlier during primary HIV infection. The course of HIV infection prior to HSI was monitored in both the source partner and recipient (8 and 11 years, respectively) and 4 years following HSI. This case report demonstrates re-infection with HIV-1 despite effective combination antiretroviral therapy.
aService of Infectious Diseases, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
bDepartments of Microbiology, Medicine and Laboratory Medicine, University of Washington School of Medicine, Seattle, Washington, USA
cLaboratory of AIDS Immunopathogenesis, Service of Immunology and Allergy
dService of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Correspondence to Erika Castro, Addiction Medicine Unit Saint Martin, Service of Community Psychiatry, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Rue Saint-Martin 7, 1003 Lausanne, Switzerland. E-mail: email@example.com
Received 28 March, 2014
Revised 5 May, 2014
Accepted 6 May, 2014