AIDS

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AIDS:
doi: 10.1097/QAD.0000000000000282
Research Letter

Immunologic status and virologic outcomes in repeat pregnancies to HIV-positive women not on antiretroviral therapy at conception: a case for lifelong antiretroviral therapy?

French, Clare E.a; Thorne, Clairea; Tariq, Shemab; Cortina-Borja, Marioa; Tookey, Pat A.a

Open Access
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Abstract

During their second pregnancy with diagnosed HIV (n = 1177), two-fifths of women in the UK/Ireland not on antiretroviral therapy (ART) at conception had an immunological indication for treatment (CD4+ <350 cells/μl), of whom nearly half had CD4+ at least 350 cells/μl in their previous pregnancy. Those initiating ART during pregnancy had a 4.3-fold increased odds of detectable viral load at delivery compared with those conceiving on treatment, suggesting that continuation of ART after pregnancy may be beneficial for many women.

© 2014 Lippincott Williams & Wilkins, Inc.

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