Skip Navigation LinksHome > April 24, 2014 - Volume 28 - Issue 7 > Innate immunity cell activation in virologically suppressed...
AIDS:
doi: 10.1097/QAD.0000000000000194
Research Letter

Innate immunity cell activation in virologically suppressed HIV-infected maraviroc-treated patients

Dentone, Chiaraa,b; Di Biagio, Antonioc; Parodi, Alessiab; Bozzano, Federicab,d; Fraccaro, Paoloe; Signori, Alessiof; Cenderello, Giovannig; Mantia, Eugenioh; Orofino, Giancarloi; De Maria, Andreab,c,j; Filaci, Gilbertob,k; Fenoglio, Danielab,k

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Abstract

This is a cross-sectional, case–control study analyzing the effect of antiretroviral therapy (ART) including or not maraviroc, on circulating monocytes and natural killer cells. Sixty-eight HIV-positive patients virologically suppressed receiving ART at least 6 months were subdivided as receiving (group 1) or not (group 2) maraviroc in their ART. Frequency of monocytes and natural killer cells, as well as their activation markers, were studied. Modulation of innate immune cells may be differently affected by combined ART.

© 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins

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