Cardiovascular risk profile was compared in 765 Italian HIV-infected outpatients enrolled in 2005 and in 765 individually age-matched and sex-matched patients enrolled in 2011. Median Framingham risk score was 8.6% in 2005 vs. 7.9% in 2011 (P = 0.04); metabolic syndrome was present in 40.3% vs. 33.4% (P = 0.006). Blood glucose, triglycerides, prevalence of smokers, and lipodystrophy were all significantly lower in 2011 (all P <0.0001). Cardiovascular risk improved over a 6-year period in Italian HIV-infected patients.
aDepartment of Infectious Diseases, Azienda Ospedaliero-Universitaria di Perugia, Perugia
bDepartment of Infectious Diseases, Pescara Hospital, Pescara
cDepartment of Infectious Diseases, Luigi Sacco Hospital, Milan
dDepartment of Infectious Diseases, University of Bari, Bari
eDepartment of Infectious Diseases, Garibaldi Hospital, University of Catania, Catania
fDepartment of Infectious Diseases, Galliera Hospital, Genoa, Genoa
gDepartment of Infectious Diseases, Careggi Hospital, Florence
hDepartment of Infectious Diseases, University of Milan, Milan
iDepartment of Infectious Diseases, San Martino Hospital Genoa, University of Genoa, Genoa
jDepartment of Infectious Diseases, Manzoni Hospital, Lecco
kUniversità di Perugia and Struttura Complessa di Medicina Interna, Azienda Ospedaliero-Universitaria di Terni, Terni, Italy.
Correspondence to Giuseppe V.L. De Socio, MD, PhD, Clinica di Malattie Infettive, Azienda Ospedaliero-Universitaria di Perugia, Piazzale Menghini 1, 06129 Perugia, Italy. Tel: +39 075 5784321; fax: +39 075 5784346; e-mail: firstname.lastname@example.org
Received 18 September, 2013
Revised 9 December, 2013
Accepted 9 December, 2013