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AIDS:
doi: 10.1097/01.aids.0000432443.22684.50
Research Letters

Evidence for continuing cross-species transmission of SIVsmm to humans: characterization of a new HIV-2 lineage in rural Côte d’Ivoire

Ayouba, Ahidjoa; Akoua-Koffi, Chantalb; Calvignac-Spencer, Sébastienc; Esteban, Amandinea; Locatelli, Sabrinaa; Li, Huid; Li, Yingyingd; Hahn, Beatrice H.d; Delaporte, Erica; Leendertz, Fabian H.c; Peeters, Martinea

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Abstract

HIV types 1 and 2 (HIV-1 and HIV-2) are the result of multiple cross-species transmissions of their simian counterparts (SIVs) to humans. We studied whether new SIVs lineages have been transmitted to humans in rural Côte d’Ivoire and identified a novel HIV-2 variant (HIV-2-07IC-TNP03) not related to any of the previously defined HIV-2 groups. This finding shows that sooty mangabey viruses continue to be transmitted to humans, causing new zoonotic outbreaks.

© 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins

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