Skip Navigation LinksHome > August 24, 2013 - Volume 27 - Issue 13 > Realtime adherence monitoring of antiretroviral therapy amon...
doi: 10.1097/QAD.0b013e328363b53f
Research Letters

Realtime adherence monitoring of antiretroviral therapy among hiv-infected adults and children in rural uganda

Haberer, Jessica E.a,b,c; Kiwanuka, Juliusd; Nansera, Denisd; Muzoora, Conradd; Hunt, Peter W.e; So, Jacquelyne; O’Donnell, Michaela; Siedner, Marka; Martin, Jeffrey N.e; Bangsberg, David R.a,b,c,d

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A real-time wireless electronic adherence monitor (EAM) and weekly self-report of missed doses via interactive voice response (IVR) and short message service (SMS) queries were used to measure antiretroviral therapy adherence in 49 adults and 46 children in rural Uganda. Median adherence was 89.5% among adults and 92.8% among children by EAM, and 99–100% for both adults and children by IVR/SMS self-report. Loss of viral suppression was significantly associated with adherence by EAM (odds ratio 0.58 for each 10% increase), but not IVR/SMS. Wireless EAM creates an exciting opportunity to monitor and potentially intervene with adherence challenges as they are happening.

© 2013 Lippincott Williams & Wilkins, Inc.


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