Out of 302 AIDS-related lymphoma (ARL) patients enrolled in the German ARL cohort study, 18 patients had plasmablastic lymphoma (PBL). Twelve out of 18 patients (67%) have died with a median survival of 4 months (range 0–11 months). In univariate analysis, an intermediate or high international prognostic index score was associated with a significantly lower overall survival and progression-free survival. The predominant cause of death was progressive lymphoma (67%). Our data indicate that the outcome of AIDS-related PBL is still very poor.
aFirst Department of Internal Medicine, University of Cologne, Cologne
bDepartment of Hematology and Oncology, Hospital Harlaching, Munich
cDepartment of Medicine I, University Medical Center Hamburg-Eppendorf, Hamburg
dDepartment of Gastroenterology, Hepatology and Infectiology, Düsseldorf University Hospital, Düsseldorf
eDepartment of Internal Medicine IV, Department of Infectious Diseases, University of Munich, Munich
fDepartment of Internal Medicine, University Hospital of Freiburg, Freiburg
gDepartment of Internal Medicine I, University of Bonn, Bonn
hICH Study Center, Hamburg/University of Schleswig Holstein, Campus Kiel, Kiel, Germany.
*Philipp Schommers and Christoph Wyen contributed equally to the writing of the article.
Correspondence to Dr Christoph Wyen, First Department of Internal Medicine, University Hospital of Cologne, Joseph Stelzmann Str. 9, 50924 Cologne, Germany. Tel: +49 221 478 3324; fax: +49 221 478 5915; e-mail: firstname.lastname@example.org
Received 23 May, 2012
Revised 9 December, 2012
Accepted 17 December, 2012