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HIV acquisition is associated with prior high-risk human papillomavirus infection among high-risk women in Rwanda

Veldhuijzen, Nienke Ja; Vyankandondera, Josephb; van de Wijgert, Janneke Ha

doi: 10.1097/QAD.0b013e32833cbb71
Research Letters

As part of a prospective cohort study to assess HIV incidence among high-risk women in Kigali, Rwanda, we evaluated the association between high-risk human papillomavirus (HPV) infection and subsequent HIV acquisition. Women who seroconverted for HIV between the first and second HPV measurement visit were 4.9 times [95% confidence interval = 1.2–19.7] more likely to have HR-HPV detected at the first visit compared with women who remained HIV-negative.

aAcademic Medical Center of the University of Amsterdam, Department of Internal Medicine, Center for Poverty-related Communicable Diseases, Amsterdam Institute of Global Health and Development, Center for Infection and Immunity, Amsterdam, The Netherlands

bCooperation Technique du Belgique (CTB)/Projet Ubuzima, Kigali, Rwanda.

Received 18 May, 2010

Accepted 2 June, 2010

Correspondence to Dr Nienke J. Veldhuijzen, Academic Medical Center of the University of Amsterdam, Department of Internal Medicine, Center for Poverty-related Communicable Diseases, Amsterdam Institute of Global Health and Development, Center for Infection and Immunity, Amsterdam, The Netherlands. Tel: +31 20 5668129/5667800; fax: +31 20 5669557; e-mail: n.veldhuijzen@amc-cpcd.org

© 2010 Lippincott Williams & Wilkins, Inc.