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Decline in human T-cell lymphotropic virus-1 prevalence in urban areas of Bissau, Guinea-Bissau: exploring the association with HIV infections

da Silva, Zacarias Ja,b; Nielsen, Jensa,e; Andersen, Andreasa; Oliveira, Inésa,e; Dias, Franciscob; Rodrigues, Amabéliaa; Holmgren, Birgittac; Andersson, Sörend; Aaby, Petera,f

doi: 10.1097/QAD.0b013e32832403e8
Research Letters

In 2006, a cross-sectional survey of 384 randomly selected houses within a community-based follow-up study was conducted to assess the human T-cell lymphotropic virus (HTLV) prevalence in Bissau. Changes in prevalence and incidence rates were assessed based on a similar survey carried out 10 years earlier. The prevalence of HTLV-1 declined significantly from 3.5% in 1996 to 2.3% in 2006. The incidence between 1996 and 2006 was only 0.9/1000 person-years and tended to be higher for women than for men.

aBandim Health Project, Indepth Network, Sweden

bNational Public Health Laboratory, Bissau, Guinea-Bissau, Sweden

cDepartment of Laboratory Medicine, Division of Medical Microbiology/Virology, Lund University, Lund, Sweden

dSwedish Institute of Infectious Disease Control, Stockholm, Sweden

eBandim Health Project, Statens Serum Institut, Denmark

fClinical Research Centre, Copenhagen University, Hvidovre Hospital, Copenhagen, Denmark.

Received 29 October, 2008

Revised 21 November, 2008

Accepted 25 November, 2008

Correspondence to Zacarias Jose da Silva, Bandim Health Project, Apt. 861, 1004 Bissau Codex, Guinea-Bissau. Tel: +245 201489; fax: +245 201672; e-mail:

© 2009 Lippincott Williams & Wilkins, Inc.