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Association of HIV infection and Mycobacterium ulcerans disease in Benin

Johnson, Roch Ca; Nackers, Fabienneb; Glynn, Judith Rc; de Biurrun Bakedano, Elisae; Zinsou, Claudea,d; Aguiar, Juliad; Tonglet, Renéb; Portaels, Françoisee

doi: 10.1097/QAD.0b013e3282f7690a
Research Letters

We investigated the association between Buruli ulcer and HIV by comparing the HIV-1/2 seroprevalence in a series of 426 Buruli ulcer patients and a sample of 613 residents of southern Benin. The overall HIV prevalence was 2.6% (11/426) among patients and 0.3% among controls (2/613), giving an odds ratio for the association between HIV and Buruli ulcer of 8.1 (95% confidence interval = 1.8–75; P = 0.003).

aBuruli ulcer National Control Program Cotonou, Benin, Belgium

bEpidemiology Unit, Catholic University of Louvain Brussels, Belgium

cInfectious Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, United Kingdom

dCentre Sanitaire et Nutritionnel Gbemoten, Zagnanado, Benin

eMycobacteriology Unit, Department of Microbiology, Institute of Tropical Medicine, Antwerp, Belgium.

© 2008 Lippincott Williams & Wilkins, Inc.