Although undesirable, immune reconstitution syndrome (IRS) indicates a favourable effect of HAART and it should be differentiated from an opportunistic infection because of their distinct implications and management. Our group analysed different immunological parameters with the aim of identifying IRS predictors in patients who begin HAART. We found that CD8+CD25+ cell pretreatment values in patients who developed IRS were four times higher than in those patients who did not develop IRS.
aDepartment of Immunology, Fundación Jimenez Díaz-Capio, Madrid, Spain
bDepartment of Infectious Diseases, Fundación Jimenez Díaz-Capio, Madrid, Spain.
Received 3 August, 2007
Revised 9 August, 2007
Accepted 13 August, 2007