Institutional members access full text with Ovid®

An outbreak of HIV-1 subtype G among Italian injecting drug users

Ciccozzi, Massimoa; Montieri, Stefaniaa; Salemi, Marcob; De Oliveira, Tulioc; Dorrucci, Mariaa; Sinicco, Alessandrod; De Luca, Andreaf; Giuliani, Massimog; Balotta, Claudiae; Rezza, Giovannia

doi: 10.1097/QAD.0b013e32813aee1a
Research Letters

We describe an outbreak of subtype G among injecting drug users (IDU) in northern Italy newly infected with HIV. We analysed pol gene sequences from samples of 139 individuals from different risk groups. Non-B subtypes were more frequently detected among IDU than in homosexual or heterosexual contacts. All G subtypes but one were found among IDU. The phylogenetic analysis indicated that the outbreak was of monophyletic origin and was caused by HIV-1 strains similar to those from western Africa.

aEpidemiology Unit Department of Infectious, Parasite and Immune-mediated Diseases, Istituto Superiore di Sanità, Rome, Italy

bDepartment of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA

cMRC Pathogen Bioinformatics Unit South African National Bioinformatics Institute, UWC, Cape Town, South Africa

dOspedale Amedeo di Savoia, Turin, Italy

eDepartment of Infectious and Tropical Diseases, Università di Milano, Milan, Italy

fPoliclinico ‘Agostino Gemelli’ Università Cattolica Roma, Rome, Italy

gOspedale ‘S. Gallicano’, Rome, Italy.

Received 7 January, 2007

Accepted 31 January, 2007

© 2007 Lippincott Williams & Wilkins, Inc.