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Nearly identical strains of human herpesvirus 8 in couples discordant for Kaposi's sarcoma

Kouri, Viviana; Marini, Alessandrab; Nambiar, Sandeepb; Rodriguez, Maria Ea; Capo, Virginiaa; Resik, Soniaa; Mantecon, Beatriza; Martinez, Ariela; Köhler-Hansner, Karin Jc; Hengge, Ulrich Rb

doi: 10.1097/QAD.0b013e328031f450
Research Letters

Transmission of human herpesvirus 8 (HHV-8) may occur through various routes including breastfeeding and sexual intercourse. We attempted to detect HHV-8 infection in nine HIV-positive couples discordant for Kaposi's sarcoma who maintained a monogamous sexual relationship for at least one year. By quantitative real-time polymerase chain reaction and HHV-8 genotyping we provide strong evidence for the sexual transmission of HHV-8 in this unique cohort.

aInstituto de Medicina Tropical ‘Pedro Kouri’, Ciudad de La Habana, Cuba, Germany

bDepartment of Dermatology, Heinrich Heine University, Düsseldorf, Germany

cJoachim Kuhlmann AIDS Foundation, Essen, Germany.

Received 17 October, 2006

Revised 15 November, 2006

Accepted 4 December, 2006

© 2007 Lippincott Williams & Wilkins, Inc.