Transmission of human herpesvirus 8 (HHV-8) may occur through various routes including breastfeeding and sexual intercourse. We attempted to detect HHV-8 infection in nine HIV-positive couples discordant for Kaposi's sarcoma who maintained a monogamous sexual relationship for at least one year. By quantitative real-time polymerase chain reaction and HHV-8 genotyping we provide strong evidence for the sexual transmission of HHV-8 in this unique cohort.
aInstituto de Medicina Tropical ‘Pedro Kouri’, Ciudad de La Habana, Cuba, Germany
bDepartment of Dermatology, Heinrich Heine University, Düsseldorf, Germany
cJoachim Kuhlmann AIDS Foundation, Essen, Germany.
Received 17 October, 2006
Revised 15 November, 2006
Accepted 4 December, 2006