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Targeted screening for primary HIV infection through pooled HIV-RNA testing in men who have sex with men

Stekler, Joannea; Swenson, Paul Da,b; Wood, Robert Wa,b; Handsfield, H Huntera; Golden, Matthew Ra,b

Research Letters

HIV-RNA testing may identify individuals with primary HIV infection. Men who have sex with men (MSM) having HIV testing through Public Health, Seattle and King County were screened for primary infection through pooled RNA testing. Eighty-one out of 3525 specimens (2.3%) had detectable antibody and RNA, and seven out of 3439 antibody-negative specimens (0.2%) had HIV RNA. Targeted screening for primary infection through pooled RNA testing in MSM is a useful addition to HIV case finding.

aUniversity of Washington, Seattle, WA, USA

bPublic Health - Seattle and King County, Seattle, WA, USA.

Received 18 March, 2005

Revised 20 April, 2005

Accepted 4 May, 2005

Sponsorship: This study was supported by Gen-Probe Incorporated. J.S. was supported by NIH grant T32 AI07140-26, M.R.G. was supported by NIH grant K23 AI01846.

© 2005 Lippincott Williams & Wilkins, Inc.