Skip Navigation LinksHome > August 1995 - Volume 9 - Issue 8 > Dual seroreactivity to HIV-1, and HIV-2 in female sex worker...
Epidemology and Social: PDF Only

Dual seroreactivity to HIV-1, and HIV-2 in female sex workers in Abidjan, Cote d'lvoire.

Ghys, Peter D.; Diallo, Mamadou O.; Ettiègne-Traoré, Virginie; Yeboué, Kouadio M.; Gnaoré, Emmanuel; Lorougnon, Félix; Teurquetil, Marie-Jeanne; Adom, Marie-Laure; Greenberg, Alan E.; Laga, Marie; De Cock, Kevin M.

Collapse Box


Objective: To determine the absolute, and proportional prevalence of dual seroreactivity to HIV-1, and HIV-2 in female sex workers in Abidjan, to determine risk determinants for this serologic profile, and to describe the associated clinical, and immunological characteristics.

Design: Cross-sectional study.

Setting: Confidential clinic for female sex workers in Abidjan.

Participants: Female sex workers.

Main outcome measures: HIV serostatus, CD4+ counts, women with AIDS, behavioural, and sociodemographic characteristics.

Results: Among 1209 women tested, the overall HIV seroprevalence was 80%, while the prevalence of dual seroreactivity was 30%. Dual seroreactivity accounted for 38% of all HIV infections. Compared with women reacting to HIV-1 only, dually seroreactive women were significantly more likely to have been in sex work for a longer period, to be aged >=20 years, and to charge less money for intercourse. No difference in mean CD4+ count was noted between women with dual seroreactivity (561+/-106/l), and HIV-1 -seropositive women (588 +/- 106/l).

Conclusions: Female sex workers in Abidjan had the highest absolute (30%), and proportional rate (38%) of dual seroreactivity yet described in any population. Increased sexual exposure is associated with an increased risk of dual seroreactivity. Although better molecular diagnostic techniques are required, a substantial proportion of female sex workers in Abidjan is likely to be infected with both HIV-1, and HIV-2.

(C) Lippincott-Raven Publishers.


Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.