From the Editor-in-Chief . . .
This issue of the Translational Journal of The American College of Sports Medicine provides a clear illustration of how basic science is translated to clinical and population application, including illustration of reverse translation of clinic to basic science. Susan Bloomfield discusses the need to confirm if findings from cell biology or the petri dish remain constant in living organisms, frequently human beings. It is well known that human biology differs considerably among individuals resulting different outcomes to identical perturbations and stimuli. Thus, of great interest is how findings from cells and animals translate to humans. Dr. Bloomfield uses several clear illustrations including the transfer of knowledge regarding bone formation in response to loading and a discussion of the NIH Common Fund initiative "Consortium for Molecular Transducers of Physical Activity," a multisite trial to collect various tissues from humans and animals to discover what, how, and why alterations to tissues and organ systems occur in response to physical activity. Included in these trials are opportunities for investigators not only to discover basic biological changes but for clinicians to provide observations to generate mechanistic research back to basic scientists—the essence of reverse translation.
The Translational Journal of The American College of Sports Medicine welcomes articles that provide the results of translational research on physical activity and exercise including policy articles that illustrate how to advocate for policy change to promote physical activity and exercise.
Joseph E. Donnelly, EdD, FACSM