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Insulin-Like Growth Factor I Signaling in Skeletal Muscle and the Potential for Cytokine Interactions

ADAMS, GREGORY R.

Medicine & Science in Sports & Exercise: January 2010 - Volume 42 - Issue 1 - pp 50-57
doi: 10.1249/MSS.0b013e3181b07d12
BASIC SCIENCES: Symposium

Recent research has demonstrated that intracellular signaling components associated with several proinflammatory cytokines have the potential to interact with signaling pathways that regulate anabolic processes in skeletal muscle. This presentation and the ensuing brief review are intended to present a selection of the potential interactions between these two critical processes.

Department of Physiology and Biophysics, University of California, Irvine, CA

Address for correspondence: Gregory R. Adams, Ph.D., Department of Physiology and Biophysics, Medical Sciences 1, Room D335, University of California, Irvine, CA 92697-4560; E-mail: gradams@uci.edu.

Submitted for publication December 2008.

Accepted for publication February 2009.

©2010The American College of Sports Medicine